Which serious cardiovascular condition may be exacerbated by the use of Sodium Bicarbonate?

The use of Sodium Bicarbonate can exacerbate heart failure primarily due to its effects on fluid and electrolyte balance. When Sodium Bicarbonate is administered, it can lead to sodium retention and increased blood volume. In patients with heart failure, the heart is already struggling to pump effectively, and additional fluid can lead to increased workload on the heart and exacerbate symptoms of heart failure, such as pulmonary congestion and peripheral edema.

Other conditions listed may have their own interactions with Sodium Bicarbonate, but heart failure is particularly sensitive to changes in fluid status and sodium balance. This makes sodium bicarbonate use particularly risky in these patients, as it can worsen their already compromised cardiac function.