Which adverse effect is associated with Metoclopramide?

Metoclopramide is a medication primarily used as an antiemetic and gastric motility agent. It works by increasing the movement of food through the stomach and intestines and can affect the central nervous system due to its dopamine receptor antagonism.

The correct choice highlights restlessness, drowsiness, and fatigue as adverse effects associated with Metoclopramide. This stems from its action on dopamine receptors, especially in the central nervous system. The blockade of these receptors can lead to extrapyramidal symptoms, which may include restlessness and an overall sense of fatigue or sedation. Therefore, the central nervous system-related side effects are important to monitor in patients receiving this medication.

Other options mention effects that are not typical or common as adverse reactions to Metoclopramide. While headaches can sometimes occur with various medications, they are not a direct or typical consequence of Metoclopramide usage. Similarly, hyperactivity is not associated with Metoclopramide, as it typically has sedative effects. Lastly, constipation is not a common adverse effect of Metoclopramide; rather, it is more likely to improve gastric motility and potentially lead to diarrhea in some cases.

Understanding the pharmacological actions and potential side effects of