Under what condition may Glucose 10% aggravate brain damage?

Glucose 10% may aggravate brain damage during head injuries and strokes due to the potential for hyperglycemia, which can contribute to neuronal injury under these conditions. When the brain is already compromised—like during a head injury or an acute stroke—elevated glucose levels can exacerbate ischemic damage by providing excessive glucose to neurons that are not capable of utilizing it efficiently due to impaired blood flow.

In scenarios such as a heart attack, respiratory distress, or cardiac arrest, although glucose may be administered depending on the clinical situation, the specific concern about aggravating brain injury aligns more closely with the context of head injuries and strokes. In these cases, uncontrolled hyperglycemia can worsen outcomes and lead to greater neuronal cell death, making it critical to monitor and manage glucose levels carefully in such patients.