In which case is adrenaline NOT indicated for use?

Adrenaline is a medication that plays a crucial role in several acute medical conditions due to its potent vasoconstrictive and bronchodilator effects. In the context of severe anxiety, the use of adrenaline is typically not indicated because it can exacerbate anxiety symptoms rather than alleviate them. Severe anxiety involves heightened physiological responses, including increased heart rate and blood pressure, which adrenaline can further stimulate. As a result, administering adrenaline in this scenario is counterproductive and can potentially worsen the patient's condition.

In contrast, adrenaline is indicated for cardiac arrest due to its ability to increase cardiac output and improve perfusion during resuscitation efforts. It is also utilized in cases of croup to reduce airway inflammation and swelling, and it is vital for the treatment of anaphylaxis, where it acts rapidly to reverse severe allergic reactions. Therefore, while adrenaline is a life-saving agent in many emergencies, its use is not appropriate in cases of severe anxiety.