In children under 16 years, which medication is contraindicated?

Frusemide is a loop diuretic commonly used in adults for conditions like heart failure and fluid overload. In pediatric patients, especially those under 16 years of age, its use can be more complicated. The primary concern with administering frusemide in this age group is the potential for electrolyte imbalances, particularly hypokalemia, which can have significant impacts on a child's developing cardiovascular system. Additionally, dosing in children is particularly sensitive, and improper dosing could lead to adverse effects or inadequate treatment.

In contrast, glucose and glucagon are medications that are generally safe and even necessary for managing specific conditions in children. Glucose is crucial for treating hypoglycemia, while glucagon is effective for severe hypoglycemic events, and both can be appropriately used in pediatric emergencies.

Thus, frusemide’s specific contraindications and heightened risk in the pediatric population highlight why it should not be administered to children under 16 years.