How does Sodium Bicarbonate affect plasma potassium levels?

Sodium Bicarbonate is known for its role in the management of metabolic acidosis, and one important effect it has is on the regulation of plasma potassium levels. When Sodium Bicarbonate is administered, it causes a shift of potassium ions from the extracellular fluid into cells. This movement is largely due to the increase in blood pH that occurs with bicarbonate administration, leading to a state where cells take in more potassium to help balance the changes in acid-base status.

This effect results in a decrease in the concentration of potassium in the plasma. Therefore, the answer indicating that Sodium Bicarbonate decreases plasma potassium levels accurately reflects this physiological response. This mechanism can be particularly significant in clinical scenarios, such as hyperkalemia (elevated plasma potassium), where Sodium Bicarbonate may be used as a therapeutic intervention to help lower potassium levels and thereby reduce the risk of cardiac complications associated with high serum potassium.